Aspirin
Meaning of Aspirin- Aspirin is acetylsalicylic acid. It is rapidly converted in the body to salicylic acid which is responsible for most of the action. It is one of the oldest analgesic and antiinflammatory drugs and is still frequently used.
Structure of Aspirin-
Formula- C₉H₈O₄
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| structure of aspirin |
What is aspirin used for -
Uses of aspirin tablet
Antipyretic(Fever)
Analgesic(Pain killer)
Anti-inflammatory
Acute Rheumatic fever
Rheumatic arthritis
Osteoarthritis
Postmyocardial infarction
Pregnancy-induced hypertension and pre-eclampsia
Patent ductus arteriosus
Familial colonic polyposis
Prevention of colon cancer
Side effect of aspirin(Adverse effect of aspirin)
Nausea
Vomiting
Epigastric distress
Peptic ulcer
Rashes
Urticarias
Asthma
Rhinorrhoea
Dizziness
Titinus
Vertigo
Mental confusion
Reye's syndrome
Mechanism of action of aspirin
It is rapidly converted into the body to salicylic acid which is responsible for most of the action. Other actions are the result of acetylation of certain macromolecules including COX.
Is Aspirin a blood thinner?
Yes, It interferes with platelet aggregation, and bleeding time is prolonged to nearly twice the normal bleeding time.
Is aspirin an Ibuprofen?
No, Ibuprofen and aspirin are different drugs.
Aspirin for Reducing Risk of Heart Attack
There is no direct effect on the Heart, But it increases cardiac output and causes peripheral vasodilation.
Sodium and water retention also occurs.
Precaution for aspirin(Contraindication of aspirin)
Aspirin contraindicated in patient with peptic ulcers
Excess bleeding tendency
Aspirin should be avoided in the diabetic patient
Avoided in children with chickenpox and Influenza
Interactions of Aspirin
Aspirin reduces protein-bound iodine levels by displacing Thyroxine.
Aspirin inhibits tubular secretion of uric acid and antagonizes uricosuric action of probenecid, Tubular secretion of methotrexate also interferes.
How long should tab aspirin be taken post covid?
It depends on the severity of covid infection or disease. As you know, coronavirus is a serious illness if the respiratory system and it will harm your body. So the duration of aspirin taken post covid is as directed by the physician.
